New Gene Discovered For Recessive Form Of Brittle Bone Disease
Researchers at the National Institutes of Health and other institutions have discovered the third in a sequence of genes that accounts for previously unexplained forms of osteogenesis imperfecta (OI), a genetic condition that weakens bones and results in frequent fractures. The newly identified gene contains the information needed to make the protein Cyclophilin B. This protein is part of a complex of three proteins that modifies collagen, folding it into a precise molecular configuration.
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Researchers have developed a simpler, faster and more accurate method than the earlier ones of determining how stress injuries might affect inanimate or human structures. The researchers take 3-D sampled or scanned data of structures and calculate the point of weakness so that preventive measures can be taken in advance.